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Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma

机译：沙利度胺维持治疗可增加老年骨髓瘤患者的无进展生存率但不能提高整体生存率

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BackgroundThalidomide maintenance therapy after stem cell transplantation resulted in increased progression-free survival and overall survival in a few trials, but its role in non-transplant eligible patients with multiple myeloma remains unclear. This study assessed the impact of thalidomide-interferon in comparison to interferon maintenance therapy in elderly patients with multiple myeloma.

机译：背景在一些试验中，干细胞移植后沙利度胺维持疗法可提高无进展生存期和总生存期，但其在非移植性多发性骨髓瘤患者中的作用尚不清楚。这项研究评估了沙利度胺-干扰素与老年多发性骨髓瘤患者的干扰素维持治疗相比的影响。

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期刊名称 Haematologica
作者
Heinz Ludwig; Zdenek Adam; Elena Tóthová; Roman Hajek; Boris Labar; Miklós Egyed; Ivan Spicka; Heinz Gisslinger; Johannes Drach; Ingrid Kuhn; Axel Hinke; Niklas Zojer;
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作者单位

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年(卷),期 2010(95),9
年度 2010
页码 1548–1554
总页数 7
原文格式 PDF
正文语种
中图分类血液学检验;
关键词
thalidomide thalidomide-interferon progression-free survival overall survival;

机译：沙利度胺;沙利度胺-干扰素;无进展生存期;总生存期;

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专利

1. Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma | Haematologica [J] . Heinz Ludwig, Zdenek Adam, Elena Tóthová, Haematologica . 2010,第9期

机译：沙利度胺维持治疗可增加老年骨髓瘤患者的无进展生存率，但不能提高整体生存率血液学
2. Association of CD117 and HLA-DR expression with shorter overall survival and/or progression-free survival in patients with multiple myeloma treated with bortezomib and thalidomide combination treatment without transplantation [J] . Wang Huan, Zhou Xin, Zhu Jian-Wei, Oncology letters . 2018,第5aPta1期

机译：CD117和HLA-DR表达的关联在多个骨髓瘤患者中具有较短的整体存活和/或无进展生存，并在没有移植的情况下使用硼佐米和沙利度胺联合治疗治疗
3. Effect of etoposide plus thalidomide as maintenance therapy on progression-free survival of elderly patients with advanced non-small cell lung cancer [J] . Yanan Ge, Zhendong Zheng, Zhaozhe Liu, 肿瘤学与转化医学（英文） . 2017,第003期

机译：依托泊苷联合沙利度胺作为维持治疗对老年晚期非小细胞肺癌无进展生存的影响
4. Association between tumor heterogeneity and progression-free survival in non-small cell lung cancer patients with EGFR mutations undergoing tyrosine kinase inhibitors therapy [C] . Jiangdian Song, Di Dong, Yanqi Huang, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2016

机译：接受酪氨酸激酶抑制剂治疗的EGFR突变非小细胞肺癌患者肿瘤异质性与无进展生存的关系
5. Association of patient-reported outcomes with progression-free survival in malignant pleural mesothelioma. [D] . Hackshaw, Michelle Denise. 2010

机译：患者报告的结局与恶性胸膜间皮瘤无进展生存的相关性。
6. Association of CD117 and HLA-DR expression with shorter overall survival and/or progression-free survival in patients with multiple myeloma treated with bortezomib and thalidomide combination treatment without transplantation [O] . Huan Wang, Xin Zhou, Jian-Wei Zhu, -1

机译：硼替佐米联合沙利度胺联合治疗未移植的多发性骨髓瘤患者CD117和HLA-DR表达与总生存期缩短和/或无进展生存期的相关性
7. Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma [O] . Ludwig, Heinz, Adam, Zdenek, Tóthová, Elena, 2010

机译：沙利度胺维持治疗可增加老年骨髓瘤患者的无进展生存率，但不能提高整体生存率

Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma

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