Isoelectric focusing of human and guinea-pig C2: polymorphism of guinea-pig C2

摘要

The isoelectric point (pI) of human and guinea-pig C2 was determined by electrofocusing. The results showed that human C2 and C2 of some guinea-pigs had a pI of approximately pH 5.5–5.6; in some guinea-pig sera C2 activity was resolved into two fractions, one with a pI of about 5.2 and the other of about 5.5. The data suggest the possibility that guinea-pig C2 may exist in at least two allotypic forms.