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Higher baseline viral diversity correlates with lower HBsAg decline following PEGylated interferon-alpha therapy in patients with HBeAg-positive chronic hepatitis B

机译：HBeAg阳性慢性乙型肝炎患者接受PEG化干扰素-α治疗后较高的基线病毒多样性与较低的HBsAg下降相关

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BackgroundViral diversity seems to predict treatment outcomes in certain viral infections. The aim of this study was to evaluate the association between baseline intra-patient viral diversity and hepatitis B surface antigen (HBsAg) decline following PEGylated interferon-alpha (Peg-IFN-α) therapy.

机译：背景技术病毒多样性似乎可以预测某些病毒感染的治疗结果。这项研究的目的是评估PEG化干扰素-α（Peg-IFN-α）治疗后，基线患者体内病毒多样性与乙型肝炎表面抗原（HBsAg）下降之间的关联。

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期刊名称 Infection and Drug Resistance
作者
Hu Li; Li Zhang; Hong Ren; Peng Hu;
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作者单位

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年(卷),期 2018(11),-1
年度 2018
页码 671–680
总页数 10
原文格式 PDF
正文语种
中图分类药学;
关键词
HBsAg decline viral diversity Shannon entropy interferon chronic hepatitis B;

机译：HBsAg下降;病毒多样性;香农熵;干扰素;慢性乙型肝炎;

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专利

1. Higher baseline viral diversity correlates with lower HBsAg decline following PEGylated interferon-alpha therapy in patients with HBeAg-positive chronic hepatitis B [J] . Hu Li, Li Zhang, Hong Ren, Infection and Drug Resistance . 2018,第1期

机译：HBeAg阳性慢性乙型肝炎患者接受PEG干扰素-α治疗后，较高的基线病毒多样性与较低的HBsAg下降相关
2. Baseline HBsAg predicts response to pegylated interferon-alpha 2b in HBeAg-positive chronic hepatitis B patients [J] . Chen Gong-Ying, Zhu Meng-Fei, Zheng Da-Liang, World journal of gastroenterology : . 2014,第25期

机译：基线HBsAg预测HBeAg阳性慢性乙型肝炎患者对聚乙二醇化干扰素-α2b的反应
3. The Predictive Value of Baseline HBsAg Level and Early Response for HBsAg Loss in Patients with HBeAg-positive Chronic Hepatitis B during Pegylated Interferon Alpha-2a Treatment [J] . LI Ming Hui, HU Lei Ping, HUA Wen Hao, 生物医学与环境科学（英文版） . 2017,第003期

机译：聚乙二醇干扰素α-2a治疗期间HBeAg阳性慢性乙型肝炎患者基线HBsAg水平和早期应答对HBsAg丢失的预测价值
4. Studies of Therapy with Thymosin α 1 in Combination with Pegylated Interferon α2a and Ribavirin in Nonresponder Patients with Chronic Hepatitis C [C] . ROBERTO CAMERINI, ALESSIA CIANCIO, ALFONSO DE ROSA, International Symposiumn on Thymosins in Health and Disease; 20070321-24; Washington,DC(US) . 2007

机译：胸腺素α1联合聚乙二醇化干扰素α2a和利巴韦林治疗慢性丙型肝炎无反应者的研究
5. Baseline HBsAg predicts response to pegylated interferon-α2b in HBeAg-positive chronic hepatitis B patients [O] . Gong-Ying Chen, Meng-Fei Zhu, Da-Liang Zheng, 2014

机译：基线HBsAg预测HBeAg阳性慢性乙型肝炎患者对聚乙二醇化干扰素-α2b的反应
6. Higher baseline viral diversity correlates with lower HBsAg decline following PEGylated interferon-alpha therapy in patients with HBeAg-positive chronic hepatitis B [O] . hu li, Li Zhang, HONG REN, 2018

机译：较高的基线病毒多样性与聚乙二醇化干扰素-α治疗患者患者患者HBEAG阳性慢性乙型肝炎患者较低的HBsAg下降相关

Higher baseline viral diversity correlates with lower HBsAg decline following PEGylated interferon-alpha therapy in patients with HBeAg-positive chronic hepatitis B

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