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Effect of felodipine on the serum lipid profile of patients with hypertension

机译:非洛地平对高血压患者血脂的影响

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摘要

Forty patients suffering from mild to moderate degree of hypertension were put on felodipine. Their lipid profile was analysed before the start of their therapy and consecutively at two and four months after starting felodipine. There was a statistically significant fall in the levels of serum cholesterol, serum triglycerides and serum total lipids; though no appreciable variation was observed in HDL and LDL cholesterol levels. At baseline there were a few patients who had higher than the normal range of the serum lipid profile. Analysis of these patients showed a highly significant fall in the levels of serum cholesterol, serum triglycerides, serum LDL-cholesterol and serum total lipids i.e. felodipine modified the lipid profiles of hypertensive patients in a positive way.
机译:40名患有轻度至中度高血压的患者接受了非洛地平治疗。在开始治疗前以及开始使用非洛地平后的两个月和四个月,对他们的血脂状况进行了分析。血清胆固醇,血清甘油三酸酯和血清总脂质水平有统计学意义的下降。尽管在HDL和LDL胆固醇水平上没有观察到明显的变化。在基线时,有几例患者的血脂水平高于正常范围。对这些患者的分析表明,血清胆固醇,血清甘油三酯,血清LDL-胆固醇和血清总脂质的水平显着下降,即非洛地平以积极的方式改变了高血压患者的脂质谱。

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