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A new way of describing meiosis that uses fractal dimension to predict metaphase I

机译:一种描述减数分裂的新方法该方法使用分形维数来预测中期I

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摘要

Meiosis, the reductive nuclear division, is a continuum, but for purposes of communication, is described in stages. In sexually-reproducing organisms, including the dwarf mistletoe Arceuthobium americanum, prophase I of meiosis is prolonged (8 months for female A. americanum). Conversely, metaphase I, where chromosome pairs line up along a dividing cell's "equator", is relatively brief, difficult to predict, but critical regarding the random distribution of the paternal and maternal chromosomes in sexual organisms. However, descriptions of meiosis as either a continuum or stages are limited to qualitative observations. A quantification of meiosis can provide mathematical descriptors and allow for the prediction of when chromosomes reach the equator; this will not only be useful to researchers of cell division, but also to those requiring a large sample of metaphase I materials. Here, the probability-density function was used to calculate the fractal dimension of A. americanum nuclei undergoing early meiosis, and it predicted the onset of metaphase I by 2 days.
机译:减数分裂是还原性核分裂,是一个连续的过程,但出于沟通目的,分阶段进行了描述。在有性繁殖的生物体中,包括矮小的槲寄生美洲Arceuthobium americanum,减数分裂的前期I延长(雌性A. Americanum为8个月)。相反,中期I(染色体对沿着分裂细胞的“赤道”排列)相对简短,难以预测,但对于父本和母本染色体在性生物中的随机分布至关重要。但是,将减数分裂描述为连续体或阶段仅限于定性观察。减数分裂的量化可以提供数学描述,并可以预测染色体何时到达赤道。这不仅对细胞分裂的研究人员有用,而且对需要大量中期I材料样品的研究人员也有用。在这里,概率密度函数被用来计算经历减数分裂的美洲念珠菌核的分形维数,并预测到中期I发生的2天。

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