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Two-staged stent-assisted angioplasty treatment strategy for severe left main coronary distal bifurcation stenosis associated with the right coronary chronic total occlusion

机译:严重的左主干远端冠状动脉远端分叉狭窄伴右冠状动脉慢性完全闭塞的两阶段支架辅助血管成形术治疗策略

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摘要

A 63-year-old female patient, with history of 8-year hypertension and 10-year hyperlipidemia, presented with severe left main coronary bifurcation stenosis (LMCS) associated with the right coronary artery chronic total occlusion (CTO-RCA). On the day of admission, she received drug treatment with aspirin, clopidogrel, heparin, statins, angiotensin converting enzyme inhibitors and β-blocker. On the next day, she underwent CTO recanalization with 6F guiding-catheter and two rapamycin-eluting stents, and showed no postoperative discomfort after interventional treatment. Considering having hypertensive nephropathy and chronic renal insufficiency, the patient then received intravenous saline full hydration therapy. Two weeks after successful completion of the RCA revascularization, the original collateral circulation in the blood flow from the LMC to RCA became two-way flow. Under the safe and reliable protective condition, staged percutaneous coronary intervention (PCI) with 6F XB3.0 guiding catheter and rapamycin-eluting stents was applied to treat the LMCL. 9-month postoperative follow-up with coronary computed tomographic imaging showed no restenosis inside the original stent, without any myocardial ischemic event. Our successful approach to turn the original unprotected LMCS combined with CTO-RCA into a protective one reduces the interventional risk and provides additional option besides coronary artery bypass graft surgery to treat such complex coronary artery disease (CAD).
机译:一名63岁的女性患者,有8年的高血压和10年的高脂血症病史,伴有严重的左主冠状动脉分叉狭窄(LMCS)和右冠状动脉慢性完全闭塞(CTO-RCA)。入院当天,她接受了阿司匹林,氯吡格雷,肝素,他汀类药物,血管紧张素转化酶抑制剂和β-受体阻滞剂的药物治疗。第二天,她用6F导管和两个雷帕霉素洗脱支架进行了CTO再通,并且在介入治疗后没有出现术后不适。考虑到患有高血压肾病和慢性肾功能不全,患者随后接受了静脉注射生理盐水完全水化治疗。在成功完成RCA血运重建的两周后,从LMC到RCA的血流中的原始侧支循环变为双向流动。在安全可靠的保护条件下,采用6F XB3.0引导导管和雷帕霉素洗脱支架进行经皮冠状动脉介入治疗(PCI),以治疗LMCL。术后9个月进行的冠状动脉计算机断层摄影术随访显示,原始支架内没有再狭窄,没有任何心肌缺血事件。我们成功的方法将原始的未保护的LMCS与CTO-RCA组合成一种保护性的方法,降低了介入风险,并提供了除冠状动脉搭桥术以外的其他选择,以治疗此类复杂的冠状动脉疾病(CAD)。

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