CERAMENT treatment of fracture defects (CERTiFy): protocol for a prospective multicenter randomized study investigating the use of CERAMENT™ BONE VOID FILLER in tibial plateau fractures

摘要

BackgroundBone graft substitutes are widely used for reconstruction of posttraumatic bone defects. However, their clinical significance in comparison to autologous bone grafting, the gold-standard in reconstruction of larger bone defects, still remains under debate. This prospective, randomized, controlled clinical study investigates the differences in pain, quality of life, and cost of care in the treatment of tibia plateau fractures-associated bone defects using either autologous bone grafting or bioresorbable hydroxyapatite/calcium sulphate cement (CERAMENT™|BONE VOID FILLER (CBVF)).