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Urachal adenocarcinoma in situ with pseudomyxoma peritonei: a case report

机译:腹膜假性黏液瘤原发性尿道腺癌1例

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摘要

A 54 year old man presented with a six month history of abdominal pain. A computerised tomography scan showed a well defined intra-abdominal unilocular mass with a calcified wall just superior to the bladder. At laparotomy, pseudomyxoma peritonei was discovered, together with a midline abdominal mass adherent to the anterior abdominal wall originating from the fundus of the bladder. The specimen consisted of a cystic mass measuring 14 × 9.5 × 7 cm overall, which contained mucoid material. Histological examination revealed that the cyst was lined by mucinous epithelium, which in areas varied from having bland morphology to showing pronounced nuclear and architectural atypia. There was abundant extracellular mucin. The specimen was extensively sampled but there was no evidence of invasion. This tumour has many unusual features, namely: the absence of destructive invasion, association with pseudomyxoma peritonei, areas of dysplasia and cystadenoma, and stromal osseous metaplasia within the wall.
机译:一名54岁的男子出现了六个月的腹痛史。电脑断层扫描显示,腹腔内的单眼肿块清晰可见,钙化壁恰好于膀胱。在剖腹手术中,发现了假性粘液瘤腹膜,并发现中线腹部肿块粘附在源自膀胱底的前腹壁上。标本由总大小为14×9.5×7 cm的囊性肿块组成,其中包含粘液样物质。组织学检查显示,囊肿由粘液上皮衬里,粘液上皮的区域从平淡无奇的形态到明显的核和建筑异型性。胞外粘蛋白丰富。标本被广泛采样,但是没有入侵的迹象。该肿瘤具有许多不寻常的特征,即:无破坏性侵袭,与腹膜假性粘液瘤相关,异型增生和囊腺瘤区域以及壁内的间质骨化生。

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