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Preventive cardiology or cardiometabolic medicine: a new and emerging subspecialty?

机译:预防心脏病或心脏素质药物:一个新的和新兴的亚特色?

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摘要

While we have seen great reductions in cardiovascular disease (CVD) morbidity and mortality over the past few decades, the rate of these declines has recently diminished, and there is even evidence that CVD mortality may be on the rise once again [ ]. Much of this is fueled by the epidemic of obesity, metabolic syndrome and type 2 diabetes [ ]. There is a wealth of evidence regarding the efficacy of cholesterol-lowering medications (particularly statins), blood pressure control, and most recently the treatment of diabetes with newer medications that positively impact CVD outcomes [ ]. Yet recent data continue to demonstrate inadequate adherence to preventive medications and inadequate control of risk factors [ , ]. Even in the case of diabetes, where CVD is the major cause of morbidity and mortality, while many patients are at reasonable targets for HbA1c, blood pressure, and low-density lipoprotein-cholesterol individually, 20% or fewer are at all three targets simultaneously, suggesting a lack of coordinated care and understanding of the priorities that should be placed to reduce CVD risk in such persons [ ]. Moreover, there is a continued rise in obesity both in developing and developed nations, with this closely linked to other cardiometabolic risk factors such as blood pressure and dyslipidemia, as well as being a strong determinant of type 2 diabetes. Consequently, there is an urgency for healthcare providers from different specialties to come together to address together the CVD risks common in many patients if we are to reduce, or at least prevent an imminent rise in CVD morbidity and mortality moving forward. While clearly there has been great progress made in the treatment of persons with known CVD, if we are to make further progress in the next few decades, there needs to be a shift in focus in cardiovascular medicine towards promoting cardiovascular health and prevention. A specialized field of preventive cardiology or cardiometabolic medicine [ ] is meant to address this need.
机译:虽然在过去的几十年中,我们看到心血管疾病(CVD)发病率和死亡率的损失很大,但最近减少了这些下降的速度,甚至有证据表明CVD死亡率可能再次增加[]。大部分这是由肥胖,代谢综合征和2型糖尿病的疫情来推动的。有关胆固醇降低药物(特别是他汀类药物),血压控制,以及最近治疗糖尿病的糖尿病的疗效存在丰富的证据,具有积极影响CVD结果的新药物[]。然而,最近的数据继续证明对预防性药物的依赖性不足,并且对风险因素的控制不足[]。即使在糖尿病的情况下,CVD是发病率和死亡率的主要原因,而许多患者则是HBA1C,血压和低密度脂蛋白 - 胆固醇的合理靶向,同时同时在所有三个靶标中进行20%或更少,暗示缺乏协调的关怀和理解应该放弃的优先事项,以减少这些人的CVD风险[]。此外,在开发和发达国家方面持续存在肥胖症,这与其他心脏血压和血脂血症如血压和血脂血症如2型糖尿病的强烈决定因素密切相关。因此,如果我们要减少,或者至少可以防止迫在眉睫的CVD发病率和死亡率致力于向前发展,不同专业的医疗保健提供者都会举起许多患者中常见的CVD风险。虽然在接下来的几十年中,在接下来的几十年中进行了进一步进展,但在涉及已知CVD的人方面取得了巨大进展,但如果我们在接下来的几十年中进一步进展,则需要在促进心血管健康和预防的心血管医学中重点转变。预防性心脏病或心脏素质药物[]的专业领域意味着要解决这种需求。

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