Efficacy and safety of corticosteroids in COVID-19 based on evidence for COVID-19 other coronavirus infections influenza community-acquired pneumonia and acute respiratory distress syndrome: a systematic review and meta-analysis

摘要

Very little direct evidence exists on use of corticosteroids in patients with coronavirus disease 2019 (COVID-19). Indirect evidence from related conditions must therefore inform inferences regarding benefits and harms. To support a guideline for managing COVID-19, we conducted systematic reviews examining the impact of corticosteroids in COVID-19 and related severe acute respiratory illnesses.