In three quarters of a century of observation and research, the effects of fluoride on dental caries and on general bodily health have been well documented. An expanding data base has allowed a firming up of the guidance and standards for appropriate and safe levels of naturally occurring fluorides for human consumption. Over time, through specific recommendations, the maximum fluoride concentrations deemed appropriate have been altered, but by a process of considered adjustment. Although the Public Health Service has been responsible for the formalization of many of the recommended standards, those recommendations have been based on research from many fronts. In the most recent reconsideration of the standards for natural fluoride, the most exhaustive and thoroughly documented review to date was done, incorporating review by representatives from State, Federal, and private programs. Although the specific example of the development of standards for natural fluoride is used, it should be illustrative of similar processes that are constantly underway in regard to substances and factors with a potential impact on the public's health. Expansion of the data base through research and scientific inquiry will lay the foundation for future reconsideration of the standards for naturally occurring fluorides.
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