The role of peripheral vascular tone in the development of hypotension induced by dialysis was investigated in eight patients undergoing haemodialysis with acetate or bicarbonate buffered fluid. Each patient had two sessions of dialysis with acetate fluid and two with bicarbonate fluid in the order acetate, bicarbonate, bicarbonate, acetate or bicarbonate, acetate, acetate, bicarbonate. Mean arterial blood pressure fell at a mean rate of 3·9 mm Hg/hour during dialysis with acetate fluid and 1·4 mm Hg/hour during dialysis with bicarbonate fluid. The rate of fall was significantly greater during dialysis with acetate fluid compared with bicarbonate fluid. Heart rate increased by a mean rate of 2·6 beats/min/hour during dialysis with both acetate and bicarbonate fluid. Vascular resistance in the forearm increased at a rate of 3·6 units/hour during dialysis with acetate fluid and 4·5 units/hour during dialysis with bicarbonate fluid, but the venous bed of the forearm dilated. The index of venous tone rose at a mean rate of 0·23 ml/100 dl over 40 mm Hg/hour during dialysis with acetate fluid and 0·20 ml/dl over 40 mm Hg/hour during dialysis with bicarbonate fluid.Inappropriate peripheral venodilatation may be important in the development of hypotension induced by dialysis.
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机译：在八名接受醋酸盐或碳酸氢盐缓冲液进行血液透析的患者中，研究了外周血管张力在由透析引起的低血压发展中的作用。每位患者接受两次乙酸盐透析，两次用碳酸氢盐透析，依次为乙酸盐，碳酸氢盐，碳酸氢盐，乙酸盐或碳酸氢盐，乙酸盐，乙酸盐，碳酸氢盐。在使用醋酸盐液体进行透析的过程中，平均动脉血压的平均下降速度为3·9 mm Hg /小时，而在使用碳酸氢盐液体进行的透析过程中，平均动脉血压的平均下降率为1·4 mm Hg /小时。与碳酸氢盐液相比，乙酸盐液透析期间的跌倒率明显更高。在使用醋酸盐和碳酸氢盐液体进行透析的过程中，心率平均提高2·6次/分钟/小时。前臂的血管阻力在用醋酸盐液透析期间以3·6单位/小时的速度增加，而在用碳酸氢盐液体透析期间以4·5单位/小时的速度增加，但前臂的静脉床扩张。在用醋酸盐液透析期间，静脉张力指数以40 mm Hg /小时的平均速率上升0·23 ml / 100 dl，在用碳酸氢盐液透析期间以40 mm Hg / hour的平均速率上升0·20 ml / dl。在透析引起的低血压发展中，静脉扩张可能很重要。
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