Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes α- and β-amyrin in a mouse model of colitis

摘要

Background and purpose:α- and β-amyrin are pentacyclic triterpenes found in plants and are known to exhibit pronounced anti-inflammatory effects. Here, we evaluated the effects of a 1:1 mixture of α- and β-amyrin (α,β-amyrin) on an experimental model of colitis in mice.