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Research paper: Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study

机译：研究论文：肌萎缩性侧索硬化症的血浆神经丝重链水平和疾病进展：一项纵向研究的见解

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摘要

ObjectiveTo investigate the role of longitudinal plasma neurofilament heavy chain protein (NfH) levels as an indicator of clinical progression and survival in amyotrophic lateral sclerosis (ALS).

机译：目的探讨纵向血浆神经丝重链蛋白（NfH）水平在肌萎缩性侧索硬化症（ALS）临床进展和生存中的作用。

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期刊名称 BMJ Open Access
作者
Ching-Hua Lu; Axel Petzold; Jo Topping; Kezia Allen; Corrie Macdonald-Wallis; Jan Clarke; Neil Pearce; Jens Kuhle; Gavin Giovannoni; Pietro Fratta; Katie Sidle; Mark Fish; Richard Orrell; Robin Howard; Linda Greensmith; Andrea Malaspina;
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作者单位

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年(卷),期 -1(86),5
年度 -1
页码 565–573
总页数 9
原文格式 PDF
正文语种
中图分类
关键词
ALS Motor Neuron Disease Neuroimmunology;

机译：ALS;运动神经元疾病;神经免疫学;

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专利

1. Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study [J] . Lu Ching-Hua, Petzold Axel, Topping Jo, Journal of Neurology, Neurosurgery and Psychiatry . 2015,第5期

机译：肌萎缩性侧索硬化症的血浆神经丝重链水平和疾病进展：一项纵向研究的见解
2. Phosphorylated neurofilament heavy chain levels in paired plasma and CSF of amyotrophic lateral sclerosis [J] . Li Siyuan, Ren Yuting, Zhu Wenjia, Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology . 2016,第Null期

机译：配对的血浆和肌萎缩性侧索硬化症的脑脊液中磷酸化的神经丝重链水平
3. Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis [J] . Tortelli R., Copetti M., Ruggieri M., European journal of neurology: the official journal of the European Federation of Neurological Societies . 2015,第1期

机译：脑脊液神经丝轻链水平：进展为广泛性肌萎缩性侧索硬化症的标志
4. A Longitudinal Study of P300 Brain-Computer Interface and Progression of Amyotrophic Lateral Sclerosis [C] . Nathan A. Gates, Christopher K. Hauser, Eric W. Sellers Foundations of augmented cognition: Directing the future of adaptive systems . 2011

机译：P300脑-计算机界面与肌萎缩性侧索硬化进展的纵向研究
5. Targeting Motor Neuron - Immune System Crosstalk to Modulate the Disease Progression in Amyotrophic Lateral Sclerosis Mouse Model [D] . Trolese, Maria Chiara. 2020

机译：靶向运动神经元 - 免疫系统串扰调节肌营养侧面硬化小鼠模型中的疾病进展
6. Cerebrospinal Fluid Neurofilament Light Chain (NfL) Predicts Disease Aggressiveness in Amyotrophic Lateral Sclerosis: An Application of the D50 Disease Progression Model [O] . Marie Dreger, Robert Steinbach, Nayana Gaur, 2021

机译：脑脊髓液神经膜轻链（NFL）预测肌营养侧面硬化症中的疾病侵袭性：D50疾病进展模型的应用
7. Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis: Neurofilament Light Chain Levels in Definite Subtypes of Disease [O] . Gaiani, Alessandra, Martinelli, Ilaria, Bello, Luca, 2017

机译：肌萎缩性侧索硬化症的诊断和预后生物标志物：疾病的确定亚型中的神经丝轻链水平

Research paper: Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study

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