首页> 美国卫生研究院文献>BMJ Open Access >Extended report: Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective randomised controlled study (SURPRISE study)

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Extended report: Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective randomised controlled study (SURPRISE study)

机译：扩展报告：类风湿关节炎对甲氨蝶呤反应不佳的患者中在甲氨蝶呤中添加托珠单抗与切换至托珠单抗的比较：一项前瞻性随机对照研究（SURPRISE研究）的52周结果

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ObjectiveTo compare the efficacy and safety between tocilizumab added to methotrexate and tocilizumab switched from methotrexate in patients with active rheumatoid arthritis (RA).

机译：目的比较加用甲氨蝶呤的托珠单抗与从甲氨蝶呤转换为托珠单抗在活动性类风湿关节炎（RA）患者中的疗效和安全性。

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期刊名称 BMJ Open Access
作者
Yuko Kaneko; Tatsuya Atsumi; Yoshiya Tanaka; Masayuki Inoo; Hitomi Kobayashi-Haraoka; Koichi Amano; Masayuki Miyata; Yohko Murakawa; Hidekata Yasuoka; Shintaro Hirata; Hayato Nagasawa; Eiichi Tanaka; Nobuyuki Miyasaka; Hisashi Yamanaka; Kazuhiko Yamamoto; Tsutomu Takeuchi;
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作者单位

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年(卷),期 -1(75),11
年度 -1
页码 1917–1923
总页数 7
原文格式 PDF
正文语种
中图分类
关键词
Rheumatoid Arthritis DMARDs (biologic) Treatment Disease Activity;

机译：类风湿关节炎;DMARDs（生物的）;治疗;疾病活动;

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1. Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study) [J] . Kaneko Yuko, Atsumi Tatsuya, Tanaka Yoshiya, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2016,第11期

机译：类风湿关节炎对甲氨蝶呤反应不佳的患者中，在甲氨蝶呤中添加托珠单抗与切换至托珠单抗的比较：一项前瞻性，随机对照研究（SURPRISE研究）的52周结果
2. Tocilizumab discontinuation after attaining remission in patients with rheumatoid arthritis who were treated with tocilizumab alone or in combination with methotrexate: results from a prospective randomised controlled study (the second year of the SURPRISE study) [J] . Kaneko Yuko, Kato Masaru, Tanaka Yoshiya, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2018,第9期

机译：在患有类风湿性关节炎的患者中停留后停止康康替纳豆，单独或与甲氨蝶呤组合治疗：令人医前随机对照研究的结果（意外研究的第二年）
3. Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY) [J] . Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2013,第1期

机译：在甲氨蝶呤反应不充分的患者中加入tocilizumab或改用tocilizumab单药治疗：一项为期2年的类风湿关节炎（ACT-RAY）随机对照策略试验的24周症状和结构结果
4. Tocilizumab discontinuation after attaining remission in patients with rheumatoid arthritis who were treated with tocilizumab alone or in combination with methotrexate: results from a prospective randomised controlled study (the second year of the SURPRISE study) [O] . Yuko Kaneko, Masaru Kato, Yoshiya Tanaka, -1

机译：类风湿性关节炎患者单独或联合甲氨蝶呤治疗的类风湿关节炎患者达到缓解后停药：前瞻性随机对照研究（SURPRISE研究的第二年）
5. Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY) [O] . Dougados, Maxime, Kissel, Karsten, Sheeran, Tom, 2013

机译：在甲氨蝶呤反应不充分的患者中添加Tocilizumab或改用Tocilizumab单药治疗：一项为期2年的类风湿关节炎（ACT-RAY）随机对照策略试验的24周症状和结构结果

Extended report: Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective randomised controlled study (SURPRISE study)

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