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Case Report: Iron deficiency anaemia in a coeliac: a cause for concern?

机译:病例报告:乳糜泻中的缺铁性贫血:值得关注吗?

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摘要

A 70-year-old woman with a 15-year history of coeliac disease was admitted for treatment and investigation of symptomatic anaemia. Of note, she was recently commenced on aspirin therapy for retinal artery occlusion. This followed a normal gastro-duodenoscopy, colonoscopy and CT abdomen as workup for iron deficiency anaemia. On this occasion, the patient was further investigated with small bowel capsule endoscopy. This revealed an ulcerated lesion in her proximal jejunum suspicious for malignancy, namely lymphoma. A biopsy of the lesion confirmed adenomatous changes and high-grade dysplasia without malignant changes. Given the endoscopic appearances of the lesion, she was further evaluated with a small bowel MRI. This revealed a 3 cm lesion with associated lymphadenopathy but no distant metastases. She proceeded to resection of her small bowel which confirmed an invasive adenocarcinoma of her proximal jejunum. She is currently undergoing adjuvant chemotherapy on an outpatient basis.
机译:一名患有乳糜泻15年病史的70岁妇女入院接受治疗和对症性贫血的调查。值得注意的是,她最近开始接受阿司匹林治疗视网膜动脉阻塞。随后进行了正常的胃十二指肠镜检查,结肠镜检查和CT腹部检查,以解决缺铁性贫血。在这种情况下,用小肠胶囊内镜进一步检查了患者。这表明她的空肠近端有溃疡性病变,可疑为恶性肿瘤,即淋巴瘤。病变活检证实为腺瘤性改变和高度不典型增生,无恶性改变。鉴于病变的内窥镜表现,她接受了小肠MRI进一步评估。这表明有一个3 cm的病变伴有淋巴结肿大,但没有远处转移。她开始切除小肠,证实其近端空肠为浸润性腺癌。她目前正在门诊接受辅助化疗。

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