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Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats

机译：临床相关剂量的异氟烷预处理可导致血红素加氧酶-1对大鼠肝缺血再灌注的保护作用。

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BackgroundActivation of heme oxygenase-1 (HO-1) has been proved to reduce damages to the liver in ischemia reperfusion injury. The objective of present study was to determine whether clinic relevant doses of isoflurane treatment could be sufficient to activate HO-1 inducing, which confers protective effect against hepatic ischemia-reperfusion injury.

机译：背景血红素加氧酶-1（HO-1）的激活已被证明可以减少缺血再灌注损伤肝脏的损伤。本研究的目的是确定临床相关剂量的异氟醚治疗是否足以激活HO-1诱导，从而赋予抗肝缺血-再灌注损伤的保护作用。

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期刊名称 BMC Gastroenterology
作者
Xin Lv; Liqun Yang; Kunming Tao; Yantao Liu; Tian Yang; Guozhong Chen; Weifeng Yu; Hao Lv; Feixiang Wu;
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作者单位

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年(卷),期 1977(11),
年度 1977
页码 31
总页数 8
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
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专利

1. Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats [J] . Xin Lv, Liqun Yang, Kunming Tao, BMC Gastroenterology . 2011,第1期

机译：临床相关剂量的异氟烷预处理可导致血红素加氧酶-1对大鼠肝缺血再灌注的保护作用。
2. Heme oxygenase-1 could mediate the protective effects of hyperbaric oxygen preconditioning against hepatic ischemia-reperfusion injury in rats [J] . LiuY., SunX.-J., LiuJ., Clinical and experimental pharmacology & physiology . 2011,第10期

机译：血红素加氧酶-1可能介导高压氧预处理对大鼠肝脏缺血再灌注损伤的保护作用
3. Heme oxygenase-1 could mediate the protective effects of hyperbaric oxygen preconditioning against hepatic ischemia-reperfusion injury in rats [J] . LiuY., SunX.-J., LiuJ., Clinical and experimental pharmacology & physiology . 2011,第10期

机译：血红素加氧酶-1可能介导高压氧预处理对大鼠肝脏缺血再灌注损伤的保护作用
4. Pegylated hemin, a water-soluble micelle with therapeutic potential against ischemia-reperfusion injury via induction of heme oxygenase-1 [C] . Jun Fang, Haibo Qin, Takahiro Seki, Annual meeting exposition of the Controlled Release Society . 2011

机译：聚乙二醇化的血红素，一种水溶性胶束，具有通过诱导血红素加氧酶-1对抗缺血再灌注损伤的治疗潜力
5. Ischemic and pharmacological preconditioning of rat myocardium: Effects on ischemia-reperfusion injury. [D] . Du, Ying. 2005

机译：大鼠心肌缺血和药理预处理：对缺血再灌注损伤的影响。
6. Heme Oxygenase-1 Induction by the Clinically Used Anesthetic Isoflurane Protects Rat Livers From Ischemia/Reperfusion Injury [O] . Rene Schmidt, Eva Tritschler, Alexander Hoetzel, 2007

机译：临床使用的麻醉异氟醚诱导的血红素加氧酶-1保护大鼠肝脏免受缺血/再灌注损伤
7. Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats [O] . Yu Weifeng, Chen Guozhong, Yang Tian, 2011

机译：临床相关剂量的异氟烷预处理可导致血红素加氧酶-1对大鼠肝缺血再灌注的保护作用。

Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats

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