Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum Foeniculum vulgare Sambucus nigra and Cassia augustifolia for chronic constipation

摘要

BackgroundA phytotherapic compound containing Pimpinella anisum L., Foeniculum vulgare Miller, Sambucus nigra L., and Cassia augustifolia is largely used in Brazil for the treatment of constipation. However, the laxative efficacy of the compound has never been tested in a randomized clinical trial. The aim of this study was to evaluate the efficacy and safety of the product.