首页> 美国卫生研究院文献>Arthritis Research >Impairment of glyoxalase-1 an advanced glycation end-product detoxifying enzyme induced by inflammation in age-related osteoarthritis

【2h】

Impairment of glyoxalase-1 an advanced glycation end-product detoxifying enzyme induced by inflammation in age-related osteoarthritis

机译：老年性骨关节炎的炎症引起乙二醛乙二醛（一种高级糖基化终产物解毒酶）受损

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundAccumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme involved in the removal of AGE precursors, especially carboxymethyl-lysine (CML). We aimed to investigate the expression of several AGEs and Glo-1 in human OA cartilage and to study chondrocytic Glo-1 regulation by inflammation, mediated by interleukin (IL)-1β.

机译：背景年龄相关的骨关节炎（OA）涉及晚期糖基化终产物（AGEs）的积累。乙二醛酶（Glo）-1是参与AGE前体尤其是羧甲基赖氨酸（CML）去除的主要酶。我们旨在研究几种AGEs和Glo-1在人OA软骨中的表达，并研究白介素（IL）-1β介导的炎症引起的软骨细胞Glo-1调节。

著录项

期刊名称 Arthritis Research
作者
Sabine Trellu; Alice Courties; Stéphane Jaisson; Laëtitia Gorisse; Philippe Gillery; Saadia Kerdine-Römer; Carlos Vaamonde-Garcia; Xavier Houard; François-Paul Ekhirch; Alain Sautet; Bertrand Friguet; Claire Jacques; Francis Berenbaum; Jérémie Sellam;
展开▼
作者单位

展开▼
年(卷),期 2019(21),-1
年度 2019
页码 18
总页数 12
原文格式 PDF
正文语种
中图分类外科学;
关键词
Aging Advanced glycation end-product Chondrocyte Osteoarthritis Glyoxalase Carboxymethyl-lysine;

机译：老化;晚期糖基化终产物;软骨细胞;骨关节炎;乙二醛酶;羧甲基赖氨酸;

相似文献

外文文献
中文文献
专利

1. ACCUMULATION OF ADVANCED GLYCATION END-PRODUCTS (AGES) IN OSTEOARTHRITIC CARTILAGE IS RELATED TO AN IMPAIRMENT OF THE ADAPTATIVE MECHANISM OF GLYOXALASE-1 [J] . Trellu S., Courties A., Jaisson S., Osteoarthritis and cartilage . 2017,第Suppla1期

机译：骨关节炎软骨中的晚期糖化末端产物（年龄）的积累与乙醛酸酶-1的适应性机制的损害有关。
2. Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals [J] . Frank Stam, Casper G. Schalkwijk, Coen van Guldener, Nephrology Dialysis Transplantation . 2006,第3期

机译：在非糖尿病患者中，晚期糖基化终产物肽与肾功能受损有关，但与内皮功能障碍和炎症的生化指标无关
3. Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals. [J] . Stam F, Schalkwijk CG, van Guldener C, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 2006,第3期

机译：在非糖尿病患者中，晚期糖基化终产物肽与肾功能受损有关，但与内皮功能障碍和炎症的生化标志无关。
4. Singlet oxygen induced advanced glycation end-product photobleaching of in vivo human fingertip autofluorescence [C] . Bin Deng, Anabel Simental, Patrick Lutz Biomedical vibrational spectroscopy V: Advances in research and industry. . 2012

机译：单线态氧诱导的体内人指尖自发荧光的晚期糖基化终产物光漂白
5. Effects of Advanced Glycation End-Products on Osteoblasts [D] . ?Mayberry, Derick E. 2020

机译：晚期糖化终产物对成骨细胞的影响
6. Diesel Particulate Matter Induces Receptor for Advanced Glycation End-Products (RAGE) Expression in Pulmonary Epithelial Cells and RAGE Signaling Influences NF-κB–Mediated Inflammation [O] . Paul R. Reynolds, Karisa M. Wasley, Camille H. Allison 2011

机译：柴油微粒物质诱导肺上皮细胞中晚期糖基化终产物（RAGE）表达的受体并且RAGE信号传导影响NF-κB介导的炎症。
7. Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals [O] . Frank Stam, Casper G. Schalkwijk, Coen van Guldener, 2005

机译：先进的糖化末端产物肽与肾功能受损，但没有患有内皮功能障碍和炎症的生物化学标志物相关，非糖尿病个体

Impairment of glyoxalase-1 an advanced glycation end-product detoxifying enzyme induced by inflammation in age-related osteoarthritis

摘要

著录项

相似文献

相关主题

期刊订阅