Revisiting spatial distribution and biochemical composition of calcium-containing crystals in human osteoarthritic articular cartilage

摘要

IntroductionCalcium-containing (CaC) crystals, including basic calcium phosphate (BCP) and calcium pyrophosphate dihydrate (CPP), are associated with destructive forms of osteoarthritis (OA). We assessed their distribution and biochemical and morphologic features in human knee OA cartilage.