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Development of a subject search filter to find information relevant to palliative care in the general medical literature

机译:开发主题搜索过滤器以查找与一般医学文献中的姑息治疗相关的信息

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摘要

>Purpose: The research developed and validated palliative care search filters for use in the general biomedical literature.>Methods: Four general medical journals were hand-searched to identify articles relevant to palliative care, forming a “gold standard” reference set. Searches comprising Medical Subject Headings (MeSH) and text-words were created for use in Ovid MEDLINE, and retrieved references were compared to the gold standard. Sensitivity, specificity, accuracy, and precision rates were calculated.>Results: By hand-searching 20,501 articles published in the 4 journals during the 3-year study period (1999–2001), reviewers identified 773 items relevant to palliative care (3.8%). A master search combining 9 MeSH descriptors with 3 text-words achieved 45.4% sensitivity, 99.3% specificity, 73% precision, and 97.3% accuracy. Efforts to increase the sensitivity by modifying 3 relevant published but unvalidated searches did not improve the yield, except in 1 case which resulted in an improved sensitivity of 56.9% but was offset by reduced specificity (92.1%), precision (22%), and accuracy (90.8%).>Conclusions: The study confirmed that literature relevant to palliative care is difficult to identify in general medical journals. While the filter developed in this research represents the best trade-off between sensitivity, specificity, accuracy, and precision, the sensitivity is unacceptably low. Further research, such as frequency analysis of text-words and MeSH terms, is required to increase the sensitivity of searching in this subset of the literature.
机译:>目的:该研究开发并验证了用于一般生物医学文献的姑息治疗搜索过滤器。>方法:人工搜索了四种普通医学期刊,以识别与姑息治疗相关的文章,形成“黄金标准”参考集。创建了包含医学主题词(MeSH)和文本词的搜索以用于Ovid MEDLINE,并将检索到的参考文献与黄金标准进行了比较。 >结果:在为期三年的研究期(1999-2001年)中,通过手动搜索4种期刊上发表的20,501篇文章,审阅者确定了773项相关姑息治疗(3.8%)。结合9个MeSH描述符和3个文本词的主搜索可实现45.4%的敏感性,99.3%的特异性,73%的准确性和97.3%的准确性。通过修改3个相关的已发表但未经验证的搜索来提高敏感性的努力并未提高产量,只有1个案例的敏感性提高了56.9%,但被特异性降低(92.1%),精确度降低(22%)和准确性(90.8%)。>结论:该研究证实,与姑息治疗有关的文献很难在普通医学期刊中找到。尽管这项研究中开发的过滤器代表了灵敏度,特异性,准确性和精密度之间的最佳折衷,但灵敏度却低得令人无法接受。需要进行进一步的研究,例如对文本词和MeSH词进行频率分析,以提高搜索在这部分文献中的敏感性。

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