Clinical imaging and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG

摘要

Clinical features of atypical DIPG (aDIPG). There was a bimodal age distribution of patients with aDIPG ( ), with a slight male predilection ( ). Fifty percent of patients had a symptom duration longer than 6 weeks at presentation ( ). The most common presenting symptoms were cranial nerve palsies ( ). Diagnostic surgical procedures performed are shown in ( ) and treatment details are shown in ( ) and ( ). Most patients experienced no or only transient complications after surgery ( ). Cranial nerve palsies were the most common complication after surgery ( ). CSI, craniospinal irradiation; CTX, cytotoxic therapy; NTR, near-total resection; Persist: persistent; RT, radiation therapy; STR, subtotal resection; TAR, targeted therapy; Trans, transient