Objective To investigate the distribution of Helicobacter pylori and drug resistance in Lishui area so as to provide references for treatment of Helicobacter pylori. Method 8357 patients underwent gastroscopy due to upper gastrointestinal discomfort were retrospective analyzesd from January 2015 to December 2017,14C breath test was used to detect Helicobacter pylori infection,gastroscopy,gastric mucosa biopsy culture of Helicobacter pylori strains. The infection of Helicobacter pylori between patients of different sex and age were compared in this area,and the antibiotic resistance of patients infected with Helicobacter pylori were analyzed. Results Among 8357 patients,2884 were positive for Helicobacter pylori,with a positive rate of 34.51%. Male patient infection rate was 36.75%(1603/4362),Female patient infection rate was 32.07%(1281/3995),the gender difference was statistically significant(P60 infection rate were 39.66% and 39.01% respectively,higher than other age groups,the difference was statistically significant(χ2=100.857,P60岁感染率分别为39.66%、39.01%,高于其他年龄段,差异有统计学意义(χ2=100.857,P50岁人群,男性感染率高于女性.对于幽门螺旋杆菌感染者,根据药敏谱进行治疗,可提高患者治愈率.
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