老年癌痛患者抑郁障碍的临床评估分析

摘要

目的 调查老年癌痛患者生活事件量表(LES)、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)及肿瘤患者生活质量评分(QOL),评估老年癌痛患者抑郁障碍的发病情况以及对生活质量的影响.方法 对104例老年癌症患者按数字评分法(NRS)、视觉模拟评分法(VAS)评分分为两组,癌痛组56例,非癌痛组48例,由一对一方式完成LES、HAMD、HAMA评分及QOL评分.结果 癌痛组抑郁障碍的发生率为78.6%,明显高于非癌痛组45.83%(P<0.01);其中癌痛组与非癌痛组相比较,中度及重度抑郁的发生率明显增高(P<0.01).癌痛通过药物有效控制后,HAMD、HAMA量表评分明显降低,HAMD量表评分与非癌痛组差异有统计学意义(P<0.01);癌痛组生活质量评分明显低于非癌痛组,差异有统计学意义(P<0.05).结论 老年癌痛患者抑郁障碍发生率高并严重影响生活质量,积极有效控制疼痛是防治老年癌痛患者焦虑抑郁的重要措施.%Objective To investigate the Life Event Scale(LES),Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale (HAMA),Quality of Life(QOL),Evaluation the Prevalence of depression of elderly patients with cancer pain and the influence on the quality of life. Methods 104 cases of elderly cancer patients were randomly divided into group,including 56 cases of cancer pain,48 cases of non cancer pain. LES,HAMD,HAMA score and QOL score of all patients were performed by one to one. Results The prevalence of depression of cancer pain group was 78.6%,which was significantly higher than that control group(45.8%)(P<0.01).Compared to non cancer pain group,the incidence of moderate and severe depression was significantly higher of cancer pain group(P<0.01).To control of cancer pain actively with the drug,the score decreased significantly of HAMD and HAMA. The quality of life of cancer pain group was significantly lower than that of the control group(P<0.05). Conclusion A higher prevalence of elderly cancer pain is found and seriously affects the quality of life. It is an important measure to control pain actively for prevention and treatment of depression anxiety in patients with elderly cancer pain.