静脉输注5葡萄糖在无痛肠镜检查中的临床意义

摘要

Objectives To explore the clinical significance of the 5% glucose injection on the anesthesia painless colonoscopy.Methods 120 patients were enteroscheoceled under intravenous anesthesia by propofol combined with small dose fentanyl. Subsequently,these patients were randomly divided into 3 groups(n=40 in each group)as follows:patients injected with 200ml 0.9% normal saline in group C;both 100ml 5% glucose and 100ml normal saline in group P;both 50ml 5% glucose and 150ml normal saline in group D. The total propofol dosage,the time from last propofol infusion to patients awaking,the colonoscopy operation time,blood glucose concentration before and after enteroscheocele were used to evaluate the effects of 5% glucose injection on the anesthesia painless colonoscopy.Results These three groups have not statistically significant(P>0.05) in the total propofol dosage,blood glucose concentration before injection,and the colonoscopy operation time. The blood glucose concentration after colonoscopy in group P significantly higher than both group C and D(P<0.05). Moreover,the awaking time in group P was obviously shorter than both group C and D(P<0.05).Conclusions The intravenous injection of 5% glucose not only effectively prevents the occurrence of hypoglycemia in colonoscopy,but also avoids prolonging time of awaking from anesthesia. Meanwhile,this method was economically feasible and not increasing the workload of medical staff.%目的 研究静脉输注5%葡萄糖注射液对无痛肠镜患者麻醉苏醒时间的影响,并评价其临床意义.方法 将120例无痛肠镜患者随机分为0.9%氯化钠200ml(C)组、5%葡萄糖100ml(P)组和5%葡萄糖50ml(D)组,每组各40例,三组患者均在丙泊酚复合小剂量芬太尼静脉麻醉下进行结肠镜检查,C组静脉输注0.9%氯化钠注射液200ml,P组静脉输注5%葡萄糖注射液100ml+0.9%氯化钠注射液100ml,D组静脉输注5%葡萄糖注射液50ml+0.9%氯化钠注射液150ml,测定患者输液前和术毕时的血糖浓度,观察停用丙泊酚至患者苏醒的时间、丙泊酚的用药总量与肠镜操作时间.结果 输液前血糖、肠镜操作时间与丙泊酚用药总量三组比较,差异无统计学意义(P均>0.05);术毕时血糖C组明显低于P组和D组,D组明显低于P组,差异有统计学意义(P均<0.05);苏醒时间C组比P组和D组明显延长,D组明显长于P组,差异有统计学意义(P均<0.05).结论 静脉输注5%葡萄糖液100ml能有效防治无痛肠镜患者低血糖的发生,避免麻醉苏醒时间的延长,且方法经济易行,不增加医护人员的工作量.