主要报道了用廉价的碳酸酯作为环合试剂来合成抗菌药利奈唑胺重要中间体口恶唑烷酮类化合物的方法,对合成工艺进行了优化,改进后的工艺收率较高,成本较低,操作简便,适合工业化生产。%A new method was reported for synthesis of the key intermediate of Linezolid by using cheap carbonate as cyclization reagent. Being well optimized, the improved process has the merits of low cost, high yield and simple operation to meet the needs of industrial production.
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