Purpose: To report the visual prognosis and longterm complications in patients with multifocal choroiditis and panuveitis (MCP). Methods: A retrospective stud y was performed with patients who met inclusion criteria for MCP at the Uveitis Clinic, Royal Victoria Hospital, McGill University, Montreal, Canada. Informatio n collected included duration of follow-up, visual acuity (VA) measured at each clinical visit, ocular and systemic treatment and ocular complications observed during follow-up. Results: Nineteen patients (37 eyes) with MCP with a mean fo llow-up of 76.9 months were studied. Kaplan-Meier survival analysis showed a d ecrease in the proportion of patients with a final VA ≥20/40 over time. Cystoid macular oedema was seen in 29.7%of the eyes and was the most frequent macular abnormality observed in our group. On the other hand, choroidal neovascularizati on was detected in only six (16.2%) of the eyes, but was related to VA < 20/200 in four of these eyes. Glaucoma was detected in 10.8%of the eyes. Cataract (po sterior subcapsular and/or nuclear) was the most common longterm complication, o ccurring in 40%of affected eyes. Cataract surgery improved the VA in 83.3%of these eyes. Conclusion: The visual acuity of patients with MCP decreases with tim e. Visual loss can occur from complications following the inflammation itself an d/or iatrogenic induced by the chronic use of corticosteroids.
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