首页> 外国专利> Methods for chronically reducing pathological inflammation in a patient and for determining the effectiveness of a chronic administration regimen for treating pathological inflammation in an individual, composition and combined therapy for chronic treatment of pathological inflammation in a patient and use of an alpha inhibitor. 4-integrin

Methods for chronically reducing pathological inflammation in a patient and for determining the effectiveness of a chronic administration regimen for treating pathological inflammation in an individual, composition and combined therapy for chronic treatment of pathological inflammation in a patient and use of an alpha inhibitor. 4-integrin

机译:用于长期减轻患者病理性炎症并确定长期给药方案治疗个体中病理性炎症的方法的方法,组合物和用于慢性治疗患者中病理性炎症的联合疗法以及使用α抑制剂。 4-整联蛋白

摘要

"METHODS TO CHRONICLY REDUCE PATHOLOGICAL INFLAMMATION IN A PATIENT AND TO DETERMINE THE EFFECTIVENESS OF A CHRONIC ADMINISTRATION SCHEME FOR TREATING A PATHOLOGICAL INFLAMMATION, COMPOSITION AND THERAPY WITH INFLAMMED PATOLOGICAL INBODY WITH PATHOBIC ALPHABILITY -4-INTEGRINE ". A method for chronically reducing a pathological inflammation of a patient by administering an agent that specifically binds to an alpha-4-integrin or a dimer comprising an alpha-4-integrin is described. The agent provided must have a binding affinity such that administration is sufficient to suppress pathological inflammation, and the agent is chronically administered to provide long-term suppression of pathological inflammation.
机译:“一种方法,用于长期减轻患者的病理性炎症,并确定一种慢性病管理方案,以病态的病原体合并病原体的病原体来治疗病理性炎症,组成和治疗。”描述了一种通过施用与α-4-整联蛋白或包含α-4-整联蛋白的二聚体特异性结合的试剂来慢性减轻患者病理性炎症的方法。所提供的试剂必须具有结合亲和力,使得给药足以抑制病理性炎症,并且长期给药该试剂以提供对病理性炎症的长期抑制。

著录项

  • 公开/公告号BR0307975A

    专利类型

  • 公开/公告日2005-01-11

    原文格式PDF

  • 申请/专利权人 ELAN PHARMACEUTICALS INC.;

    申请/专利号BR20030307975

  • 发明设计人 JULIE TAYLOR;TED A. YEDNOCK;

    申请日2003-02-25

  • 分类号A61K39/395;C07K16/28;

  • 国家 BR

  • 入库时间 2022-08-21 22:18:36

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