在儿童中静脉注射唑来膦酸的短期安全性评估

摘要

The clinical side effects of the potent new bisphosphonate zoledronic acid in children are unknown. In this study of 34 children with various bone disorders, the frequency of postinfusion flulike illness, hypocalcemia, and hypophosphatemia was 85% , 74% , and 82% , respectively. No renal side effects were detected after up to 3 consecutive infusions.