叶黄素治疗年龄相关性黄斑变性的临床研究

摘要

目的:观察叶黄素治疗年龄相关性黄斑变性的临床疗效.方法:采用随机、对照、双盲方法,观察83例患者服食叶黄素咀嚼片前后137只眼睛视力、眼底黄斑变化.结果:治疗组显效11眼,有效31眼,无效32眼,总有效率56.76%;对照组显效0眼,有效19眼,无效44眼,总有效率30.16%.2组比较有统计学意义(P<0.001).结论:叶黄素对年龄相关性黄斑变性患者眼底表现及视力有一定改善作用.%Objective:To evaluate the clinical therapeutic effect of Lutein on the treatment of age related macular degeneration ( AMD). Methods: 137 eyes of 83 AMD patients were randomized in a controlled , double blind trial. The treatment group was treated with lutein chewable tablets and the control group were treated with placebo . After 3-month treatment, the changes of distant vision and puncta lute - um in OCT were observed. Results:The total effective rate of the treatment group was 56.76% , significant better than 30. 16% of the control group (P <0. 001). Conclusion: Lutein showed therapeutic effect for age related macular degeneration , such as improving visual activity, elimination of retina edema and atrophying.