基于Microtox技术（微毒测试）的中药综合毒性快速评价

摘要

Microtox technology is one of the fastest testing methods for determining the poisonous or toxic substances which use Lumi -nous bacteria as a indicator organism .Our research reviews the development of microtox technology , and application for testing toxicity of Chinese medicinal materials , including technical methods , technical maps , key issues and scope of work .Our research serves as foun-dation for establishing a new safety and risk analysis system by providing a fast test method of TCM toxicity .%Microtox技术（微毒测试）是以一种非致病的明亮发光杆菌作指示生物，以其发光强度的变化为指标，测定环境中有害有毒物质的生物毒性的一种方法，现已成为一种简单、快速的生物毒性检测手段。本文综述了Microtox技术（微毒测试）的研究现状，并就该技术在中药毒性评价应用的技术方法、技术路线、关键问题以及应用范围等方面开展研究，为建立一种新的中药毒性快速检测、安全性评价以及风险分级评定的的综合评价体系奠定基础。