精灸联合匹维溴铵治疗脾肾阳虚证腹泻型肠易激综合征的临床疗效

摘要

Objective:To observe clinical efficacy of pure moxibustion combined with pinaverium bromide in spleen and kidney deficiency type of irritable bowel syndrome with diarrhea (IBS-D).Methods:Eighty patients were randomly divided into a control group and a treatment group (40 patients for each) by random number table method,and the control group received pinaverium bromide treatment while the treatment group extra pure moxibustion.The treatment course was 6 weeks for both groups.The clinical effect before and after treatment was observed together with the main symptoms (abdominal pain,diarrhea,bloating,defecation and pulpy stools).IBS Quality of Life Questionnaire was used for the evaluation of two groups (emotion,sleep,diet,daily activities and work).Results:The total effective rate of the control group was 77.50％ and the treatment group 95.00％,the treatment group better than that of the control group;Symptom scores of the treatment group were significantly lower than that of the control group,however,scores of quality of life were significantly higher.Conclusion:Pure moxibustion combined with pinaverium bromide has significant effect in irritable bowel syndrome with diarrhea,and improves the quality of life of patients.%目的:观察精灸联合匹维溴铵治疗脾肾阳虚证腹泻型肠易激综合征的临床疗效.方法:选取2014年5月至2016年3月广州市第一人民医院中医科和消化科门诊收治的符合纳入标准的患者80例,按随机数字表法分为对照组和观察组,各40例,对照组给予常规西药匹维溴铵进行治疗,观察组在此基础上给予精灸治疗,疗程均为4周.观察各组临床疗效及治疗前后主要症状(腹痛、腹泻、腹胀、排便次数、稀烂便)积分变化;采用肠易激综合征(Irritable Bowel Syndrome,IBS)生命质量问卷评价2组生命质量水平(情绪状态、睡眠状况、饮食情况、日常活动、工作情况).结果:对照组临床总疗效为77.50％,观察组为95.00％,观察组优于对照组;观察组临床各症状积分明显低于对照组;生命质量评分明显高于对照组.结论:精灸联合匹维溴铵对脾肾阳虚证腹泻型肠易激综合征有显著疗效,并可提高患者生命质量.