高磷血症致慢性肾脏病血管钙化的研究及治疗进展

摘要

血管钙化是心血管疾病中最常见的病理表现,已经成为慢性肾脏病(Chronic Kidney Disease,CKD)的主要死亡原因,也是慢性肾脏病心血管疾病高发的独立危险因素,高磷血症是慢性肾脏病的常见并发症,高磷可通过多种机制或途径参与血管钙化的发生发展,与慢性肾脏病心血管死亡率密切相关,本文就高磷血症引起血管钙化的机制及中西医治疗作一综述.%Cardiovascular disease has become the leading cause of death among patients with chronic kidney disease (CKD), and vascular calcification is the most commonly seen pathological change.Vascular calcification is an independent risk factor in cardiovascular disease induced by CKD.Hyperphosphatemia is a common complication of chronic kidney disease.High phosphorus can participate in the development of vascular calcification through a variety of mechanisms or pathways.And it is closely related to the mortality of patients with CKD and cardiovascular.In this paper, the vascular calcification mechanism caused by hyperphosphatemia and its treatment in western medicine and Traditional Chinese medicine are reviewed.