Objective: To investigate the effect of psychological intervention for reliving hemodialysis patients' pain because of internal fistula puncture. Methods: All 120 cases suffering from long-term hemodialysis and internal arteriovenous fistula plasty were divided into the control group and the treatment group with 60 cases in each group by sampling random numbers. The patients in the control group were given the conventional nursing while in the treatment group the patients were added the positive psychological intervention besides the traditional methods. The treatment periods for both groups were two months. Results: Before the intervention the scores of symptoms like de-pression and anxiety, pain, fatigue and loss of appetite compared presented no significance difference between the two groups (P>0.05) and were decreased significantly after the intervention and the comparisons of each group it-self had statistical meaning (P<0.05). After the intervention, the scores of physiological conditions, body pain and overall health of the patients were significantly higher in the treatment group, compared to the control group; the dif-ference in the two groups showed statistical meaning (P<0.05). Conclusion: Psychological interventions used in hemodialysis fistula patients can effectively alleviate the situation of anxiety and depression, reduce the needling pain to contribute to the improvement of patients' life quality.%目的：探讨心理行为干预对血透患者内瘘穿刺疼痛的影响。方法：将长期维持血液透析与动静脉内瘘成形术患者120例按照随机数字表法分为治疗组与对照组各60例，对照组患者予常规护理，治疗组患者在此基础上给予积极的心理行为干预，2组干预周期为2个月。结果：2组患者干预前焦虑抑郁与疼痛、疲劳和食欲下降症状评分比较差异无统计学意义（P＞0.05)，干预后评分明显下降，同时组间干预后评分比较差异有统计学意义(P＜0.05)。干预后治疗组患者生理机能、生理职能、躯体疼痛与总体健康评分明显高于对照组，差异有统计学意义(P＜0.05)。结论：心理行为干预应用于血透内瘘患者能有效缓解焦虑抑郁情况，减轻穿刺疼痛，有利于提高生存质量。
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