ObjectiveThis study aims to evaluate the effect of customized titanium mesh, which was designed by mirror imaging and rapid prototyping technique, with Medpor applied for orbital fracture with enophthalmos. Methods Orbital axial, coronal, and sagittal CT scan, and three-dimension CT examination were performed routinely in 18 cases of orbital fracture with enophthalmos preoperatively. Based on the CT data, prosthesis model was designed by reverse engineering and rapid prototyping technique. The customized titanium mesh and Medpor were applied for orbital reconstruction and enophthalmos correction. Orbital reduction and globe projection were evaluated by postoperative CT scan and clinical follow-up visits. Results CT scans revealed that the customized titanium mesh with Medpor had great accuracy to reconstruct the orbital fracture and correct the enophthalmos in all patients without serious complications. The eye and facial appearance and func-tion recovered significantly. No serious complication occurred in the operation and after operation. Conclusion The custo-mized titanium mesh, based on mirror imaging and rapid prototyping technique, can accurately reconstruct the orbital fractures with enophthalmos. The application of Medpor can effectively correct enophthalmos and eyeball mobility malformation.%目的：应用镜像与快速成型技术制作个性化钛网重建眼眶，在钛网上植入多孔高密度聚乙烯（Medpor）矫正眼球内陷，评价其治疗效果。方法对18例眼眶骨折患者术前行眼眶轴位、冠状位及矢状位CT扫描及三维重建，以CT数据为基础，应用快速成型技术制备实体模型，在其上制作个性化预成形钛网，术中植入钛网行眼眶重建，并在钛网基础上充填Medpor矫正眼球内陷。术后复查眼眶CT，检查钛网植入位置、眼及面部外形和眼功能。结果术后复查CT，18例患者的个性化预成形钛网均能精确地重建骨折的眼眶，眼及面部外形和眼功能显著恢复。术中术后均未发生严重并发症。结论基于镜像与快速成型技术的个性化预成形钛网技术可以精确地重建骨折及伴有骨缺损的眼眶，在钛网上植入Medpor可有效矫正眼球内陷及眼球下移畸形。
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