Objective To investigate the predictors for rapid postoperative recovery from general anesthesia ( GA) in children less than three-year old receiving repair of cleft lip or palate. Methods Totally 314 children less than three years old, who received repair of cleft lip or palate under GA in Peking Union Medical Collegc Hospital from Jan 2013 to Dec 2016, were divided into two groups according to the time from extubation to discharge from operation room and back to ward. Rapid recovery from GA were defined as the recovery time less than 30 min. All the records, inclu-ding demographics, preoperative coexist diseases, the parameters of anesthesia and operation, were compared between these two groups. The multivariate logistic regression analysis was used to survey the potential risk factors. Results When compared with the rapid recovery group, children in the non-rapid recovery group had significantly smaller age, lower body weight, smaller tracheal tube ID, less proportion of cleft palate repairment, and higher rate of preoperative respiratory coexist diseases ( P<0. 01) . The multivariate logistic regression analysis showed that preoperative respiratory coexist diseases was the independent predictors for non-rapid recovery from GA ( OR=5. 622, 95％ CI=1. 650～19. 158) . Conclusion Preoperative respiratory coexist diseases is an independent predic-tors for non-rapid recovery from GA in children <3 years old receiving repair of cleft lip or palate.%目的 分析3岁以内小儿行全麻下唇腭裂修补术全麻后快速恢复的相关影响因素.方法 回顾性分析北京协和医院2013年1月—2016年12月3岁以内行全麻下唇腭裂修补术患儿314例,根据患儿拔除气管导管至满足麻醉恢复室离室标准返回病房的时间是否超过30 min,将患儿分为快速恢复组和非快速恢复组,比较2组患儿一般资料、术前合并疾病、手术麻醉相关资料等,并对可能影响术后快速恢复的因素进行多因素Logistic回归分析.结果 与快速恢复组比较,非快速恢复组的患儿月龄较小(P<0.01)、体重较低(P<0.01)、气管插管ID号偏小(P<0.01)、腭裂修补术比例较低(P<0.01)、术前合并呼吸系统异常比例较高(P<0.01).多因素Logistic回归分析显示患儿术前合并呼吸系统异常(OR=5.622,95％CI=1.650～19.158)是术后无法快速恢复的独立预测因素.结论 术前合并呼吸系统异常是3岁以内患儿全麻下行唇腭裂修补术术后无法快速恢复的独立危险因素.
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