2011-2014年我院住院患者抗菌药物的使用情况分析

摘要

目的：分析2011—2014年本院住院患者抗菌药物（注射剂）的使用情况，为临床合理使用抗菌药物提供依据。方法：调取2011—2014年本院住院患者抗菌药物的使用信息并进行汇总，对抗菌药物的品种、销售金额、用药频度（DDDs）、日均费用（DDC）及药品排序比（B／ A）进行统计学分析。结果：2011—2014年抗菌药物的销售金额比例前3年连续下降，2014年有小幅上升；抗菌药物的品种数基本稳定；头孢菌素类和青霉素类及其复合物连续4年的销售额和 DDDs分别排名第一和第二位；多数种类的抗菌药物的 B／ A 值＜1；阿莫西林钠舒巴坦钠连续4年的 DDDs 排名第一位，同种药品不同年份的 DDC 值略有差异，多数药品的 DDC 值＞100元。结论2011—2014年本院抗菌药物的使用基本规范合理，抗菌药物的使用逐年下降，与此同时也发现一些问题，还需进一步规范。%Objective:To analyze the utilization of antimicrobial drugs(Injection)for inpatients in Tianjin Hospital from 2011 to 2014 ,and to provide reference for rational use of drugs in clinic. Methods:The utilization of antimicrobial drugs for inpatients in Tianjin Hospital from 2011 to 2014 was analyzed by defined daily doses(DDDs),defined daily cost(DDC)and drug sequence ra-tio(B/ A)statistically. Results:The proportion of the amount of sales of antibiotics declined in the first three years but increased slightly in 2014. The types of antibiotics did not change. Cephalosporins and penicillins and complex sales and DDDs for four con-secutive years ranked first and second place. B/ A for most species of antibacterials was less than 1. Amoxicillin sulbactam ranked first in DDDs and DDC of the drug varied with a little,DDC values for most drugs were greater than 100. Conclusion:In general , the utilization of antibacterial drugs in Tianjin Hospital from 2011 to 2014 is up to reasonable standard. There are also some prob-lems,which need further efforts to strengthen the management.