目的：评价地塞米松（DXM）加入阻滞麻醉中对阻生智齿拔除术后患者生活质量的影响。方法选取120例下颌阻生智齿拔除患者，采用随机数字表法将患者分为试验组和对照组，每组60例。其中试验组术前将2%利多卡因4 mL+地塞米松1 mL(5 mg)混合后将其中的3 mL行局部麻醉注射阻滞牙槽神经。对照组术前单独使用2%利多卡因3 mL行下牙槽神经阻滞麻醉。2组患者术后生活质量由智齿拔除术后症状严重度量表（PoSSe量表）评价，分析并比较2组得分。结果试验组的PoSSe量表总得分为18.0591±13.2109，低于对照组的27.8193±15.7169（P＜0.05）。试验组饮食、语言、肿胀、疼痛及日常生活积分均低于对照组（P＜0.05）。结论下颌阻生智齿拔除前加入地塞米松在局部阻滞麻醉中可降低患者术后不良反应，提高了患者的生活质量。%Objective To investigate the effect of dexamethasone addition in block anesthesia before surgery on postoperative quality of life after extraction of impacted mandibular wisdom teeth. Methods Using a random number table, 120 cases of patients were divided into experimental and control groups, each group contains 60 cases whose mandibular wis⁃dom tooth will be extracted. Before the surgery, the experimental group patients perform local block anesthetic injection with 3 mL out of 5 mL mixture of 2%lidocaine 4 mL+dexamethasone 1 mL (5 mg) to block nerve. The control group was given block anesthesia of inferior alveolar nerve with 3 mL of 2%lidocaine block anesthesia alone. Improved postoperative symp⁃toms severity scale (PoSSe) was used to evaluate patients’quality of life after tooth extraction comprehensively and quantita⁃tively by analysis and comparison of the two sets of scores. Results The experimental group’s PoSSe scores were 18.059 1 ± 13.210 9, which was lower compared with control group (27.819 3 ± 15.716 9). In experimental group, diet, language, swelling, pain and daily points were lower than the control group (P<0.05). Conclusion Topical application of dexamethasone in mandibular wisdom tooth extraction reduces postoperative adverse reactions in a certain degree and im⁃prove postoperative quality of life.
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