目的：探讨羟苯磺酸钙联合甲钴铵在治疗糖尿病神经性病变中的临床效性。方法收集本院2014年10月—2016年3月期间收治的140例具有对称性、远端糖尿病神经性病变患者的临床资料，随机分为治疗组和对照组，治疗组(n=70)采用羟苯磺酸钙联合甲钴铵治疗；对照组(n=70)则单用甲钴铵治疗。治疗周期为12周，而后观察两组患者在治疗前后总体症状评分(TTS)和神经功能障碍评分(NDS)的变化来比较临床疗效。结果经过12周治疗，治疗组患者TSS评分(7.7±2.1)分、NDS评分(7.6±2.2)分，均明显优于对照组(P<0.05)，各组病人均对治疗耐受，安全性良好。在TSS中改变最明显指标为“疼痛”，差异有统计学意义(P<0.01)。结论羟苯磺酸钙联合甲钴铵治疗糖尿病周围神经病变效果明显，是治疗糖尿病神经性病变的一种有效途径。%Objective Explore the hydroxyl benzene sulfonic acid calcium combined a cobalt ammonium in clinical ef-fect in the treatment of diabetic neurogenic lesions. Methods Collect our hospital October 2014 to March 2016 during the month of 140 patients having symmetrical distal diabetic neuropathy clinical data of patients were randomly divided into treatment and control groups,, the treatment group (n = 70) with hydroxyl benzene sulfonic acid calcium in combi-nation with a cobalt ammonium treatment; The control group (n = 70), a cobalt ammonium treatment alone. Treatment cycle for 12 weeks, and then observe two groups of patients in general symptom scores before and after the treatment (TSS) and nerve dysfunction score (NDS) to compare the clinical efficacy of change. Results After 12 weeks of treat-ment, patients treated with TSS score (7.7 ± 2.1) points, NDS score (7.6 ± 2.2) points, significantly better than the con-trol group (P<0.05), each group patients are resistant to treatment, and good security. Change in the TTS indicators for the "pain", the most obvious difference has the remarkable significance (P< 0.01). Conclusion Hydroxy benzene sul-fonic acid calcium in combination with a cobalt ammonium treatment of diabetic peripheral neuropathy effect is obvi-ous, is an effective way to treat diabetes neurologic lesions.
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