Prognosis of surgery in multilocular cystic renal cell carcinoma (report of 22 cases)

摘要

To evaluate the prognosis of surgery in multilocular cystic renal cell carcinoma (MCRCC).Methods The characteristics of prognosis of surgery in 22 MCRCC cases out of 482 cases of renal cell carcinoma were reviewed.The MCRCC cases accounted for 4.56% of the renal cell carcinoma cases with a male-to-female ratio of 2.67∶1 n the same period.The mean age of the 22 patients was 47 years (age range,32-74 years).Results Of the 22 cases,18 underwent radical nephrectomy and 4 partial nephrectomy.The diameter of the tumors ranged 1.8-11.0 cm (mean 4.8 cm).Histological examination showed that 21 cases were of clear cell carcinoma and 1 of clear cell carcinoma mixed with granular cell carcinoma.Pathological staging showed pT1N0M0 in 19 cases (86.4%),pT2N0M0 in 2 (9.1%) and pT3bN0M0 in 1(4.5%).The classification by tumor nuclear grading system showed 5 cases (23%) of G1 and 17(77%) of G2.Twenty patients were followed up for 9-56 months (mean,27.6 months) and 2 were lost of follow-up.Of the 20 patients,19 survived with no evidence of cancer and 1 died of intercurrent disease (upper gastrointestinal massive hemorrhage due to hepatocirrhosis).Conclusion MCRCC represents a distinct subtype of renal cell carcinoma.It is usually with low grade,low stage and is found incidentally.Our results indicate that MCRCC can be cured by surgery.Regardless of tumor size,the prognosis of MCRCC is favorable.12 refs.