According to the practical reservoir characteristics of the study area,the feasibility of horizon-tal wells development was analyzed,and the result showed that the reservoir characteristics of study area were suit to develop horizontal wells. Based on the establishment of three-dimensional fine geological modeling of study area,using numerical simulation,the well network pattern,length of the horizontal section,well spac-ing,row spacing and development indicators were predicted. The simulation result showed that the optimal well network was the symmetrical horizontal section,and the horizontal well had echelonment horizontal sections tra-versing the two layers of Mawu12 and Mawu13,and the well spacing and row spacing were both 2 100 m. The re-sult of development indicators prediction showed that,after 10 years,the recovery percentage was 48.78 %, which was 16.6%higher than that of vertical wells. The study result can guide the study area to develop efficiently.%根据研究区实际的储层特点，对水平井开发的可行性进行了分析。结果表明，陕100井区马五1+2储层地质条件适合水平井开发。在对研究区三维精细地质建模的基础上，采用数值模拟对水平井的井网方式、水平段长度、井排距、开发指标等进行了预测。结果表明，最优的井网形式是水平段平行对称布置，采用同时穿越马五12和马五13的阶梯状水平段的水平井，井距和排距均为2100 m。预测第10年年末，阶梯状水平井的采出程度为48.78%，比直井的采出程度高16.6%，研究结果可以指导研究区水平井的高效开发。
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