地佐辛与间苯三酚合用治疗结石性肾绞痛疗效分析

摘要

目的：观察地佐辛与间苯三酚合用治疗结石性肾绞痛临床疗效。方法肾绞痛患者178例，分为两组。实验组94例，组肌注地佐辛5mg，静脉滴注间苯三酚120mg；对照组84例，肌注杜冷丁50mg，静滴山莨菪碱10mg；观察解痉、镇痛效果及其不良反应。结果实验组和对照组总有效率分别为91.5％、89.3％，组间无显著性差异（ P＞0.05）；实验组、对照组6 h内疼痛再发率分别为13.8％、33.3％，组间有显著性差异（P＜0.05）；实验组和对照组的不良反应发生率分别为22.3％、47.6％，组间有显著性差异（P＜0.05）。结论地佐辛与间苯三酚合用治疗肾绞痛疗效好，不良反应少。%OBJECTIVE To investigate the clinical effects of dezocine combined with pholroglucinol on renal colic caused by calculus.METHODS 178 cases of renal colic patients were divided into experiment group ( n=94 ) and control group ( n=84 ).Experiment group:intramuscular dezocine 5 mg combined with intravenous pholro-glucinol 120mg.Control group: intramuscular demerol 50mg combined with intravenous anisodamine 10 mg.Spasmolysis effects ,analgesia effects and side effects in each group were observed.RESULTS There were no significant differences in total effective rate which were 91.5%,89.3%in experiment group and control respectively ( P>0.05 ) ,and statistically significant differences in the incidences of side effects which were 22.3%and 47.6%in experiment group and control respectively ( P<0.05 ).CONCLUSION There are remarkable clinical effects and low incidence of side effect of dezocine combined with benzene three phenol on renal colic caused by calculus .