不同频率电针足三里防治大鼠运动性疲劳的实验研究

摘要

Objective：To explore the prevention and cure effects of different frequency electro-acupuncture at Zusanli on rats with exercise-induced fatigue.Methods： Fifty rats were randomly divided into 5 groups： quiet group（group A）,exercise group（group B）,60min exercise group（group C）,exercise electro-acupuncture 1（group D） and exercise electro-acupuncture 2（group E）.To establish an exercise-induced fatigue model of rats by increasing load exercise.acupuncture frequency 2/15Hz and 2/100Hz were respectively used to group D and group E.To observe the changes of cortisone,testosterone,MDA and SOD.Results： Compared with group A,the cortisone was significantly improved and testosterone was significantly reduced in other groups（P0.05）,Compared with group C,the MDA was significantly reduced and SOD was significantly improved in electro-acupuncture groups（P 0.05）.Compared with group E,the MDA was reduced and SOD was improved in group D.And the SOD was with significant difference（P0.05）.Conclusions： Electro-acupuncture at Zusanli can effectively prevent and therapy exercise-induced fatigue.The effects were different with different frequency.2/15Hz frequency electro-acupuncture had a better effect.%目的：探讨不同频率电针疗法对运动性疲劳的防治作用。方法：将50只大鼠随机分成5组,分别为安静组（A组）、运动即刻组（B组）、运动后60min组（C组）、运动＋电针1组（D组）、运动＋电针2组（E组）,采用递增负荷跑台运动建立运动性疲劳大鼠模型,D组和E组分别采用2/15Hz、2/100Hz不同针刺频率进行干预,测定各组大鼠血清皮质酮、睾酮以及丙二醛（MDA）、超氧化物歧化酶（SOD）的变化。结果：与安静组比较,其余各组皮质酮（C）均明显升高,睾酮（T）显著降低,血清T/c比值具有显著性（P〈0.05）;与单纯运动C组比较,电针干预组血清MDA均降低,SOD均升高,差异具有显著性（P〈0.05）;电针干预组组间比较,运动＋电针1组（D组）较运动＋电针2组（E组）血清MDA降低,SOD升高,其中血清SOD具有显著性差异（P〈0.05）。结论：电针足三里能有效防治运动性疲劳。不同频率针刺对运动性疲劳的防治效应不同,2/15Hz频率针刺效果优于2/100Hz频率针刺。