电针联合舍曲林治疗创伤后应激障碍的效果观察

摘要

Objective To observe the effects and safety of electric acupuncture combined with sertraline in the treatment of post- traumatic stress disorder(PTSD). Methods 50 patients with post - traumatic stress disorder were randomly divided into the com-bined group and the control group. Patients in combined group were treated with sertraline and electric acupuncture(30 min/ day, 5 days per week). Patients in control group were only treated with sertraline. Two groups were treated for 4 weeks. Before and after the treatment,the patients were tested by the PTSD Checklist(PCL)and Hamilton Anxiety Scale(HAMA). Results After 4 weeks’ treatment,the PCL total score,reproduce scores,avoidance scores,hyperarousal scores and HAMA scores were lower than before treatment in two groups,and the differences were statistically significant(P < 0. 05). The PCL total score,reproduce scores,hyperar-ousal scores and HAMA scores of the combined group decreased more obviously than the control group,and the difference was statisti-cally significant(P < 0. 05). Conclusion Electric acupuncture combined with sertraline can increase the effect of treatment in repro-duce hyperarousal and anxiety symptoms in PTSD.%目的：观察电针联合舍曲林对创伤后应激障碍（PTSD）的疗效及安全性。方法将50例 PTSD 患者随机分为研究组（舍曲林联合电针治疗）和对照组（舍曲林治疗）各25例，均治疗4周。于治疗前和治疗4周末采用创伤后应激障碍检查表（PCL）及汉密尔顿焦虑量表（HAMA）评定疗效。结果共47位患者完成研究，两组治疗4周末 PCL 总评分、重现、回避、高警觉、HAMA 评分均较治疗前低，差异有统计学意义（P ＜0.05）；研究组治疗4周末 PCL 总评分、重现、高警觉、HAMA 评分低于对照组，差异有统计学意义（P ＜0.05）。结论在舍曲林基础上联用电针治疗，能够增加舍曲林对 PTSD 的重现、高警觉核心症状和焦虑症状的疗效。