Objective To observe the clinical effect of Huangqi Zhusheye in the treatment of early diabetic nephropathy.Methods This study included 61 patients with early diabetic nephropathy. They were further divided into two subgroups randomly, and treated with regular modern medicine. The treatment group (31 cases)was treated to Huangqi Zhusheye , one time everyday for 3 weeks, the control group (30 cases)only treated with regular modern medicine. Results After treatment, the fast glucose of the treating group was ( 7. 11 ± 1.02) mmol/L, PG2h was ( 10. 97 ± 1.4) mmol/L , the fast glucose of the control group was (8.06 ± 1.23 )mmol/L, PG2h was ( 11.57 ± 1.70). The β2-MG of the treating group was (0. 27 ± 0. 06) μg/L, UAER was (64. 0 ± 11.8) μg/min,the β2-MG of the control group was (0. 33 ±0. 10 ) μg/L,UAER was(71.2 ± 16. 2) μg/min. Compared to control group, the treatment group were better at decreasing blood glucose and uromicroalbunminuria. Conclusion Huangqi Zhusheye can offer good clinical treating for early diabetic nephropathy.%目的 探讨黄芪注射液联合西药基础治疗对早期糖尿病肾病的临床疗效.方法 将61例早期糖尿病肾病患者随机分为治疗组31例和对照组30例,两组均采用西医基础治疗,同时,治疗组给予黄芪注射液50ml配生理盐水250ml,1次/d,连续滴注3周.结果 治疗组治疗后空腹血糖为(7.11±1.02)mmol/L,早餐后2h血糖为(10.97±1.4)mmol/L,对照组空腹血糖为(8.06±1.23)mmol/L,早餐后2h血糖为(11.57±1.70)mmol/L;治疗组治疗后β2-MC为(0.27±0.06)μg/L,UAER为(64.0±11.8)μg/min,对照组治疗后β2-MG为(0.33±0.10)μg/L,UAER为(71.2±16.2)μg/min,治疗组与对照组比较,治疗组患者血糖水平及尿微量清蛋白明显下降.结论 黄芪注射液治疗早期糖尿病肾病临床疗效良好.
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