目的 探讨血浆灌流联合胆红素吸附治疗妊娠合并重型肝炎的临床效果. 方法 妊娠合并重症肝炎患者60例随机分为两组,对照组采取血浆灌流联合血浆置换,观察组在此的基础上再联合胆红素吸附治疗. 结果 治疗后,观察组在TBil、PT、TC、产科及内科并发症、母婴结局等指标较对照组均有显著性改善,差异有统计学意义( P<0. 05 ) ,而ATPP、ALB、FPG两组差异无统计学意义(P>0. 05). 结论 血浆灌流联合胆红素吸附治疗妊娠合并重型肝炎效果值得肯定,可有效改善肝功及凝血功能,降低并发症发生率,减少产后出血量,改善母婴结局.%Objective To explore the diagnosis and treatment of plasma perfusion combined bilirubin adsorption pregnan-cy with the clinical effect of severe hepatitis. Methods Pregnancy with 60 patients with severe hepatitis were randomly divided into two groups, control group take the plasma perfusion in combination with plasma exchange, the observation group on the basis of this combined bilirubin adsorption treatment again. Results Post treatment, the observation group in TBil, and PT, TC, ob-stetric and medical complications, and outcomes measures such as the control group were improved significantly ( P <0. 05 ) , while ATPP, propagated, FPG no difference between the two groups (P>0. 05). Conclusion Plasma perfusion combined bili-rubin adsorption treatment of pregnancy with fulminant hepatitis effect is positive, it can effectively improve the hepatic function and coagulation function, reduce complications, reduce postpartum blood loss, improve and outcomes.
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