目的 观察项八针治疗卒中后轻度认知障碍的疗效.方法 采用随机对照试验研究的设计方案,按随机数字表将200例符合标准的患者随机分为项八针组和药物组,每组100例.所有患者均接受基础药物治疗,项八针组给予针刺项八穴,穴取风池、风府、大椎和"项四花穴",药物组口服尼莫地平片,共治疗8周,治疗结束后3个月时进行随访.治疗前后分别用简易精神状态检查量表(MMSE)、蒙特利尔认知评估量表(Mo CA)及日常生活活动能力量表(Barthel指数)对两组患者进行评价.结果 治疗4周后、8周后及随访时,两组MMSE、MoCA及Barthel指数评分均较治疗前改善(P<0.01,P<0.05);与药物组比较,项八针组治疗后各观察时间点MMSE评分均优于药物组(P<0.01,P<0.05),MoCA及Barthel指数评分则于治疗4周后无明显差异(P>0.05),治疗8周及随访时优于药物组(P<0.01).结论 项八针能有效改善卒中后轻度认知障碍患者的认知功能.%Objective To observe the therapeutic efficacy of eight nape needle therapy in treating mild cognitive impairment (MCI) after cerebral stroke. Method By following a randomized controlled trial design, 200 eligible patients were randomized into an eight nape needle group and a medication group by the random number table, with 100 cases in each group. The patients all received basic medications, while the eight nape needle group was additionally intervened by acupuncture at the eight nape acupoints including Fengchi (GB20), Fengfu (GV16), Dazhui (GV14) and Xiangsihua points (Extra), and the medication group additionally received oral administration of nimodipine. The intervention lasted eight weeks, followed by a three-month follow-up. Before and after treatment, the two groups of patients were evaluated by Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) and Barthel Index (BI). Result Respectively at four-week and eight-week treatment and the follow-up, the scores of MMSE, MoCA and BI showed improvements compared with the corresponding baseline (P<0.01, P<0.05);compared with the medication group, the eight nape needle group was superior to the medication group comparing the MMSE score at each time point after treatment (P<0.01, P<0.05); there were no significant differences in the MoCA and BI scores between the two groups at four-week treatment (P>0.05), but the differences were significant at eight-week treatment and the follow-up (P<0.01). Conclusion Eight nape needle therapy can effectively improve the cognitive function in patients with MCI after cerebral stroke.
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