目的 观察刺络放血疗法配合消风散治疗血虚风燥型慢性荨麻疹的临床疗效.方法 将150例血虚风燥型慢性荨麻疹患者随机分为治疗组和对照组,每组75例.治疗组采用刺络放血疗法配合口服消风散治疗,对照组采用单纯口服消风散治疗.治疗4星期后,观察两组治疗前后各项血清学指标(IgE、嗜酸性粒细胞值、C3、C4、IL-2、IL-4)的变化情况,并比较两组临床疗效.结果 治疗组总有效率和愈显率分别为100.0％和86.7％,对照组分别为80.0％和52.0％,两组比较差异均具有统计学意义(P<0.05,P<0.01).治疗组治疗后各项血清学指标与同组治疗前比较,差异均具有统计学意义(P<0.05).对照组治疗后IgE、嗜酸性粒细胞值及IL-2、IL-4水平与同组治疗前比较,差异均具有统计学意义(P<0.05).两组治疗后各项血清学指标比较,差异均具有统计学意义(P<0.05).结论 刺络放血疗法配合消风散是一种治疗血虚风燥型慢性荨麻疹的有效方法,能改善患者血清学指标.%Objective To observe the clinical efficacy of collateral-pricking bloodletting therapy plusXiao Feng San in treating chronic urticaria due to blood deficiency and wind dryness.Method A total of 150 patients with chronic urticaria due to blood deficiency and wind dryness were randomized into a treatment group and a control group, 75 cases each. The treatment group was intervened by collateral-pricking bloodletting plus oral administration ofXiao Feng San, while the control group was intervened by oral administration ofXiao Feng San alone. Before and after 4-week treatment, the serum indexes [immunoglobulin E (IgE), eosinophil count, C3, C4, interleukin (IL)-2, IL-4] of the two groups were observed, and the clinical efficacies were also compared.Result The total effective rate and markedly effective rate were respectively 100.0％ and 86.7％ in the treatment group versus 80.0％ and 52.0％ in the control group, and the between-group differences were statistically significant (P<0.05,P<0.01). After the treatment, the serum indexes were significantly changed in the treatment group (P<0.05). The levels of IgE, eosinophil count, IL-2 and IL-4 were significantly changed after the treatment in the control group (P<0.05). There were significant differences in comparing the serum indexes between the two groups after the intervention (P<0.05).Conclusion Collateral-pricking bloodletting therapy plusXiao Feng San is an effective method in treating chronic urticarial due to blood deficiency and wind dryness, and it can improve the serum indexes.
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