血栓预防策略对高危因素妇科围术期患者下肢深静脉血栓的预防效果研究

摘要

目的:研究血栓预防策略对有高危因素妇科围术期患者下肢深静脉血栓的预防效果,为临床诊疗提供依据.方法:选取有下肢深静脉血栓高危因素的妇科围术期患者200例为研究对象,根据随机数字表法将患者均分为观察组和对照组,每组100例,其中对照组患者给予常规的压力梯度弹力袜+围手术期干预指导措施预防患者围手术期下肢深静脉血栓形成,观察组患者在对照组的基础上加用低剂量肠溶阿司匹林口服治疗预防下肢深静脉血栓,比较两组患者的预防效果之间的差异情况.结果:观察组患者干预治疗后其下肢深静脉血栓形成的例数为2例、下肢深静脉血栓发生率2.0%,明显的小于对照组患者的11例、11.0%,两组比较差异具有统计学意义(P<0. 05);观察组患者干预治疗后其D-二聚体水平为(1.3±0.2),明显的小于对照组患者的(3.1±0. 3),两组比较差异具有统计学意义(P<0.05).观察组患者术后无肺栓塞发生率,对照组患者术后1例肺栓塞发生.观察组患者干预治疗后其平均住院时间(10.3 ± 2.1)d、下肢肿胀发生率1.0%、血栓性静脉炎0例,明显的小于对照组患者的(15.6 ± 2.6)d、下肢肿胀发生率11.0%、血栓性静脉炎6.0%,两组比较差异具有统计学意义(P<0.05).结论:妇科围手术期患者需要早期积极给予下肢静脉梯度减压弹力袜、下肢深静脉血栓形成预防干预措施以及低剂量阿司匹林等相关预防干预措施,并且注意监测患者的凝血功能等相关指标,可以有效的预防围手术期患者下肢深静脉血栓的发生率,提高患者的围手术期安全性.%Objective:To study the preventive effect of thromboprophylaxis strategies for high-risk factors in perioperative gynecologic perioperative patients with deep venous thrombosis and provide evidence for clinical diagno-sis and treatment.Methods:200 gynecological perioperative patients with high risk factors of deep vein thrombosis of the lower extremities were selected as the study subjects.The patients were divided equally into the observation group and the control group according to the random number table method.100 patients in each group,and the con-trol group received routine The pressure gradient elastic stockings + perioperative intervention guidance to prevent perioperative patients with deep venous thrombosis in the lower extremities,the observation group patients in the control group plus Low-dose enteric aspirin to prevent deep vein thrombosis of the lower extremities,compared the preventive effect between the two groups of patients The difference situation.Results:In the observation group,the number of cases of deep venous thrombosis in the lower extremities was 2.The incidence of deep venous thrombosis in the lower extremities was 2.0% in the observation group,which was significantly smaller than that in the control group(11 cases,11.0%).The difference between the two groups was statistically significant.The significance(P<0.05)can be compared;the patients in the observation group had a D-dimer level of(1.3 ± 0.2)after intervention therapy,which was significantly smaller than the control group of(3.1 ± 0.3).The difference between the two groups was statistically significant(P< 0.05),can be compared.The incidence of pulmonary embolism was not ob-served in the observation group.One case of pulmonary embolism occurred in the control group.In the observation group,the average length of hospital stay was(10.3 ± 2.1)days after the intervention,the incidence of lower ex-tremity swelling was 1.0%,and thrombophlebitis was 0.It was significantly smaller than the(15.6 ± 2.6)days of the control group,and the incidence of leg swelling was 11.0%.Thrombotic veins were observed.Inflammation was 6.0%.The difference between the two groups was statistically significant(P<0.05).Conclusion:Patients with gynecological perioperative need to actively provide early-stage venous gradient decompression stockings for the lower extremities,prevention interventions for deep vein thrombosis of the lower extremities,and preventive interventions such Low-dose enteric aspirin ths,and monitor the relevant indicators such as coagulation function of patients.The prevention of the incidence of deep venous thrombosis of the lower extremities in perioperative patients and the im-provement of the perioperative safety of patients have a certain significance in clinical practice.