Objective :To explore the effect of integrated traditional Chinese and western medicine on the therapeutic effects of atherosclerosis (APN) ,high-sensitivity C-reactive protein (hs-CRP) and carotid artery plaque in patients with cer-ebral infarction .Methods :A total of 104 patients with acute cerebral infarction were selected as the study subjects .They were divided into experimental group and control group according to the random number table method .Each group had 52 patients .The patients in the control group were treated with routine treatment .The patients in the experimental group were treated with integrated Chinese and western medicine .The APN and hs-CRP levels before and after the intervention of the two groups of patients were compared .The NIHSS scale and daily life were used .The ability scale (ADL) was used to as-sess the pre and post-intervention livelihoods of the two groups of patients ,and the carotid intima-media thickness of the bi-lateral common carotid artery (CCA) and the internal carotid artery origin (ICA) before and after intervention of the two groups of patients ( (IMT) values for comparison .Results :There was no significant difference in APN and hs-CRP levels between the two groups before the intervention (P＞0 .05).After the intervention ,the APN level of the experimental group was higher than that of the control group ,and the level of hs-CRP was lower than that of the control group ( P＜0. 05).There was no significant difference in NIHSS and ADL scores between the two groups before intervention (P＞0.05). After the intervention ,the NIHSS score of the experimental group was lower than that of the control group ,and the ADL score was higher than that of the control group (P＜0 .05).There was no significant difference in IMT between the two groups before the intervention (P＞0.05).After the intervention ,both IMT values in the experimental group were lower than those in the control group (P＜0 .05).Conclusion :The combination of TCM and western medicine can significantly improve the clinical symptoms of acute cerebral infarction ,adjust the level of serum factor ,and soften the carotid plaque .%目的:探究针刺配合西药治疗对脑梗死患者治疗效果及脂联素(APN) 、超敏C反应蛋白(hs-CRP)及颈动脉斑块的影响.方法:选取104例急性脑梗死患者为研究对象,按照随机数字表法将其均分为观察组和对照组,每组各52例,对照组患者实施常规治疗,观察组患者实施针刺配合西药治疗,对两组患者干预前后的APN及hs-CRP水平进行对比,使用美国国立卫生研究院卒中量表(NIH-SS)量表及日常生活能力量表(ADL)对两组患者干预前后生活能力进行评估,并对两组患者干预前后双侧颈总动脉(CCA)及颈内动脉起始处(ICA)的颈动脉内膜中层厚度(IM T )值进行评估对比.结果:①干预前两组患者APN及hs-CRP水平对比差异无统计学意义(P＞0.05) ,干预后观察组APN水平高于对照组,hs-CRP水平均低于对照组(P＜0.05) ;干预前两组NIHSS及ADL评分对比差异无统计学意义(P＞0.05) ,干预后观察组NIHSS评分低于对照组,ADL评分高于对照组(P＜0.05) ;干预前两组CCA及ICA处IM T值对比差异不具有统计学意义( P＞0.05) ,干预后观察组两处IM T值均低于对照组(P＜0.05) .结论:针刺配合西药治疗能够显著改善急性脑梗死临床症状,调整期血清因子水平,软化颈动脉斑块.
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